The Giant leaf frog (Phyllomedusa bicolor) is a member of the tree frog family, Hylidae. They are found in the rain forest in South America specifically the countries of Bolivia, Brazil, Colombia, Ecuador, French Guiana, Guyana, Peru, Suriname, and Venezuela.
The females of the species grow larger than the males, reaching 4.3 – 4.7 inches long while the males only reach 4.05 inches long. The frogs spend their lives in the trees and even reproduce there. They lay their eggs on leaves of trees that over hang the water. After 8 days, the eggs drop into the water.
The Giant leaf frog contains some interesting peptides. They are deltorphin, deltorphin I, deltrophin II, and dermophin. They are natural opioids that are 30-40 times more potent that morphine and are theoretically be less likely to produce drug tolerance and addiction.
(credit to http://seancrane.com/galleries/bolivia for the image)